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He catalogs isolation from everyone close
"He has put my brothers far from me. My acquaintances are wholly estranged from me.
My relatives have gone away. My familiar friends have forgotten me.
Those who dwell in my house, and my maids, count me for a stranger. I am an alien in their sight.
I call to my servant, and he gives me no answer; I beg him with my mouth.
My breath is offensive to my wife. I am loathsome to the children of my own mother.
Even young children despise me. If I arise, they speak against me.
All my familiar friends abhor me. They whom I loved have turned against me.
My bones stick to my skin and to my flesh. I have escaped by the skin of my teeth.