Shared ground
Job ends this part of the debate by rejecting his friends’ “comfort” as empty and untrue (explicit). His question (“How can you…?”) is not a request for information but a dismissal of what they are offering as help (explicit). The verse assumes that words meant to comfort can fail if they do not connect to what is actually happening (inference from Job’s stated reason).
The closing line also summarizes the breakdown: even after Job’s extended argument in chapter 21 about the prosperity of many wicked people, the friends’ “answers” have not changed in a meaningful way (explicit/strongly implied by “still/remains”).
Where interpretation differs
Some readers take “falsehood” to mean their statements are factually wrong about how life works (for example, that the wicked are always quickly judged). Others take “falsehood” to mean something more like moral distortion: they are misrepresenting Job or God, even if some general principles they use can be true in other cases.
A smaller difference concerns scope: whether Job condemns everything they have said as false, or whether he targets their main claim that suffering reliably proves wrongdoing.
Why the disagreement exists
The key word “falsehood” can cover both error about facts and deceitful or misleading framing, and Job’s line is brief. Also, “your answers” can be heard as a total verdict on their speeches, or as a verdict on what remains at the core of their replies.
What this passage clearly contributes
This verse functions as Job’s closing evaluation: their counsel is “empty words” () rather than real comfort (explicit). The reason is that their replies “remain” marked by “falsehood” (explicit). In the flow of Job 21, the verse reinforces that the dispute is not merely emotional; it is also about whether the friends’ explanation fits observed reality (explicit within the chapter’s context).