Shared ground
Paul speaks as part of a ministry team (“we”), and he frames their message as an urgent appeal, not a neutral update. That matches the flow from the prior section where God’s appeal is said to come “through” Paul and his co-workers (2 Corinthians 5:20).
The passage assumes the Corinthians have truly “received the grace of God,” yet it warns that this reception can still turn out “in vain”—real grace received can become ineffective or wasted in its outcome. That is an explicit claim of the text, even though the exact failure mode is not spelled out.
Paul quotes Scripture (from Isaiah) about God listening and helping at the right moment, then he presses its point with repeated “behold” and “now.” His core emphasis is timing: God’s “acceptable time” and “day of salvation” are not presented as distant or theoretical, but as a present moment requiring a real response.
Where interpretation differs (only where needed)
“Working together” with whom? Some read Paul as saying the ministry team works together with God in God’s mission. Others read it as the team working together with each other (or as fellow-workers in the same cause), with God’s role assumed in the background. Either way, the next line focuses on the Corinthians’ response, not on elevating the team.
What does “receive … in vain” mean? Some understand it mainly as failing to embrace the message in a lasting, faithful way—initial acceptance that later becomes empty through drift, compromise, or refusal to be reconciled. Others hear a narrower warning about not rejecting Paul’s apostolic ministry (and so not benefiting from the grace God brought through that ministry). The text itself clearly warns about a wasted outcome, while leaving the concrete shape open.
How broad is “now”? Some take “now” as a general statement about the whole era of the gospel: the promised time of God’s saving help has arrived and remains open. Others hear it more specifically as “now” for the Corinthians in their situation with Paul—this is their decisive moment to respond appropriately. The passage can plausibly carry both senses: a decisive era has arrived, and a decisive moment confronts this church.
Why the disagreement exists
The wording is brief and can naturally be connected in more than one way. “Working together” does not specify its partner, and “in vain” does not list the behaviors that would make grace ineffective. Also, Paul moves quickly from Isaiah’s “acceptable time” to his own repeated “now,” and readers differ on whether that “now” is mainly about salvation-history (the new era) or about the Corinthians’ immediate crisis (or both).
What this passage clearly contributes
It portrays grace as something that must be genuinely received and not allowed to become fruitless. It frames God’s saving help as arriving at an appointed, favorable moment, and it uses Scripture to intensify urgency. The passage also shows Paul’s understanding of ministry as cooperative and persuasive: he pleads, supports the plea with Scripture, and locates the stakes in the present—“now” as the decisive time and “now” as the day of salvation.