Shared ground
This passage portrays Jerusalem like a person who cannot stay on her feet. The text explicitly says she has drunk a “cup” from Yahweh’s hand that brings staggering, and she has drained it fully. The result is not private sadness but visible collapse: people lie in the streets, and the city has no one able to steady her.
The suffering is described in overlapping pairs: ruin of the city (“desolation and destruction”) and ruin of life within it (“famine and the sword”). The imagery is communal and generational: “sons” are present in large numbers, yet none can guide or take her hand.
The passage also makes an explicit link between disaster and God’s anger: the cup is “wrath,” and the people are “full of” Yahweh’s fury and God’s rebuke. That is part of the text’s explanation of why Jerusalem is in this condition.
Where interpretation differs
What the “cup” refers to. Some read the cup language as mainly poetic description of Jerusalem’s experience of collapse and terror (a metaphor for judgment). Others think it points more directly to concrete historical events (siege, starvation, conquest), with the metaphor functioning as a summary of those realities.
Who “sons” are. Some take “sons” as the city’s children and citizens in general—its population weakened and unable to help. Others hear a sharper focus on leadership (those expected to guide), so the point is not only weakness but also a leadership vacuum.
How the “two things” relate to the four terms. Some read the four terms as two matching pairs that explain the “two things.” Others see the wording as intensifying the picture rather than offering a neat count.
Why the disagreement exists
The passage combines vivid poetry with concrete street-level details. That makes it natural to ask how tightly the imagery maps onto specific events and groups. Also, the language (“sons,” “two things”) can work at multiple levels—family metaphor, city-population, and public leadership—without the text explicitly narrowing it to only one.
What this passage clearly contributes
It contributes a portrait of judgment experienced as helpless disorientation and public ruin, not merely as an abstract idea. It insists that Jerusalem’s collapse is comprehensive (“none among all her sons”) and that the calamity includes both deprivation and violence. It also sets up the next unit’s reversal by showing Jerusalem as emptied out—having already drained the cup—so that any coming change would have to come from outside her remaining strength (see the immediate continuation in Isaiah 51:21–23).